The best known anti-aging supplement
The discovery of deprenyl’s anti-aging
properties has been around for a few decades. Originally developed as an anti-depressant (hence the name of
'deprenyl'), deprenyl's other more valuable benefits have been gradually discovered and tested.
50 × 5mg tablets
Deprenyl is a compound that was discovered approximately 40 years ago, by Dr Joseph Knoll and
colleagues, in Hungary, as they sought to develop a good anti-depressant drug. After conducting a two-year lifespan
study on rats using the drug, they were convinced of deprenyl's antiaging propeties. Since then, many other
lifespan studies on deprenyl have been conducted in other countries, most of which have to one extent or another
confirmed Dr Knoll's findings.
Europe under the trade names Eldepryl and Jumex, Deprenyl inhibits an enzyme found in the brain called monoamine
oxidase B (or MAO-B). Like most enzymes, MAO-B has only one goal: it breaks down dopamine and other compounds known
as their name suggests, are chemicals that transmit signals from one nerve cell to another; essentially,
neurotransmitters play a major role in how the human brain works.
chemically related to phenetylamine (PEA), a substance found in chocolate and produced in higher-than-normal
amounts in the brains of people who are "in love".
Deprenyl was first used in late Eighties with
extraordinary success on patients with Parkinson’s disease. In this capacity, deprenyl often
spectacularly improved the quality of Parkinson’s patients lives, which is far more important than merely providing extra time
for the patients to suffer.
life-extension experts agree that aging causes the progressive reduction of the brain chemical dopamine. A
depletion of dopamine causes: loss of energy and coordination, depression, loss of sex drive, Parkinson and
Alzheimer diseases, and accelerated aging. By replenishing brain dopamine levels, many of the adverse effects of
aging can be prevented and reversed. Deprenyl can
restore dopamine to youthful levels.
Since the publication
of Alastair Dow’s first
book on deprenyl (The Deprenyl Story), in Canada 1990, there have been many studies that confirm and extend the evidence of
deprenyl’s remarkable life-extension benefits.
Alastair Dow subsequently published his second,
more comprehensive Deprenyl book, "DEPRENYL: The Anti-Aging Drug". This book provides further evidence that
deprenyl may be beneficial in the treatment of a wide variety of neurological disorders, as well as being effective
in slowing the underlying loss of brain cells that occurs in "normal" aging.
Numerous experiments have in different ways confirmed Dr Knoll’s original findings that this
remarkable drug not only extends life but does so while improving the quality of life in many crucial
Furthermore, treatment with deprenyl has also been found to dramatically increase the lifespan
and improve the quality of life of patients with Parkinson’s and Alzeheimer’s
The evidence is
quietly growing that deprenyl is the best anti-aging drug known to man whose wonders continue to unfold as
scientists prove its multifaceted activity.
How Safe is
Life extensionists who have been taking a 5mg tablet of deprenyl every day for the past several
or more years have experienced increased energy, mood elevation, improved memory and higher sex drive - mostly
without any undesirable side effects.
Others have been taking deprenyl for anti-aging purposes and some as a mild aphrodisiac. While
these are people who take deprenyl on their own volition, after reading about both anecdotal and experimental
evidence on deprenyl's anti-aging benefits, they’re unconcerned because they’re sure deprenyl is extremely safe, as
there has been no reports of serious side effects.
Buy Deprenyl in tablets and liquids format
Deprenyl products, Cyprenil and Selepryl, have been now replaced by new liquid Deprenyl product
- Dep-Pro. When you
click Buy It Now button you will be automatically taken to the Dep-Pro order page. By clicking on images, you will
be taken to product information pages.
- May extend
lifespan - Deprenyl medication may improve the quality of
life in the latter decades, delaying the time of natural death and decreasing the susceptibility to age-related
disease - Although the evidence for a beneficial effect of
selegiline on patients with Alzheimer's disease is promising there is not yet enough evidence to recommend its
use routinely in practice. Selegiline HCl, 10 mg per day has been reported to improve attention and episodic
memory in early Alzheimer's disease.
- An effective
antidepressant - At doses of between 10 and 40 mg a day,
deprenyl has been shown to improve depression particularly when psychomotor retardation is prominent and
- Facilitates recovery after
stroke - Selegiline (deprenyl) seems to be beneficial after
a cerebral infarction. This benefit may be due to the enhancement of the recovery
- May aid in smoking
cessation - Selegiline decreases cigarette craving,
especially during abstinence, and also reduces number of cigarettes smoked. Smoking satisfaction ratings are
also reduced during the smoking sessions both before and after the brief abstinence
- Protects vascular and neuronal
tissue - Deprenyl is unique in that it demonstrates
protective effects on both vascular and neuronal tissue. Prophylactic use of low doses of deprenyl may accord
protection against vascular and neurodegenerative diseases associated with aging.
- Neuroprotection by
deprenyl - Deprenyl and related compounds may protect
neurons from apoptosis (cell death) and be applicable to delay the deterioration of neurons during advancing
ageing and in neurodegenerative disorders.
- Enhanced sexual
performance – Life-long treatment with deprenyl enhanced the
sexual and learning performance of laboratory rats and prolonged their life.
disease - Selegiline HCl, 10 mg per day has been reported to
improve attention and episodic memory in Parkinson's disease. Selegiline also improves motor reaction times in
Parkinson's and subjective feelings of increased vitality, euphoria and energy.
- Prolongs life in elderly
dogs - Specifically with respect to dogs, research findings
suggest that daily oral administration of 1 mg (per kg of weight) of L-deprenyl prolongs life when begun in
relatively healthy dogs 10-15 years of age. The administration of deprenyl should be maintained for the
duration of the dog’s life, or in any event for no less than six months.
"Deprenyl is what good pharmaceuticals are all about. First it is exceptionally safe, second it
protects and enhances mental function, mood and even libido, thirdly, it may even extend
- Julian Whitaker M.D. Health and Healing Newsletter
HOW TO BUY
Deprenyl is available to order in multiples of
100 x 5mg tablets pack size. There is also liquid deprenyl, known as Cyprenil or Selepryl, available in 300mg
bottles. Click here to buy
Deprenyl in both
liquid and tablets form.
[The above article is for information and research purposes
only. None of the above information should be misconstrued as a health or